Compound Characterization Using Gene Microarrays

Monitoring gene expression using DNA microarrays.

The concurrent development of high-density array technologies and the complete sequencing of a number of microbial genomes is providing the opportunity to comprehensively and efficiently survey the transcription profile of microorganisms under different conditions and well-defined genotypes. Microarray-based studies are uncovering broad patterns of genetic activity, providing new understanding ...

Gene Selection for Cancer Classification using Microarrays

Microarrays allow biologists to better understand the interactions between diverse pathologic states at the gene level. However, the amount of data generated by these tools becomes problematic. New techniques are then needed in order to extract valuable information about gene activity in sensitive processes like tumor cells proliferation and metastasis activity. Recent tools that analyze microa...

Gene Expression Studies Using Affymetrix Microarrays

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Bacterial gene expression analysis using microarrays.

Characterization of Influenza Vaccine Immunogenicity Using Influenza Antigen Microarrays

BACKGROUND Existing methods to measure influenza vaccine immunogenicity prohibit detailed analysis of epitope determinants recognized by immunoglobulins. The development of highly multiplex proteomics platforms capable of capturing a high level of antibody binding information will enable researchers and clinicians to generate rapid and meaningful readouts of influenza-specific antibody reactivi...